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The overall clinical significance is limited

Although the higher dose of acetyl-l-carnitine did not improve survival (adjusted odds ratio [aOR] 1.18, 95% CI 0.463.02), the lower dose did (aOR 0.27, 95% CI 0.100.71)

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Russell Article Foreshock-induced slip transients set mainshock nucleation timing Analysis of laboratory experiments using a rate-and-state-based Griffith-like rupture framework shows that foreshocks can regulate mainshock nucleation timing, with larger foreshocks generating higher transient sliding velocities and triggering a more rapid transition to dynamic rupture